New chapter section on various forms of spinocerebellar ataxiaĬlarification in text and figures of regional alterations in the overall distribution of ventilation and perfusion referred to as V̇/Q̇ mismatch, including concepts of anatomic versus alveolar (wasted ventilation) dead space and right-to-left shunt New chapter section on urticaria (perivascular dermatitis) New figure illustrating iron transport and regulation in the duodenal enterocyte ![]() Totally revised chapter on neoplasia, including 19 new figures and 4 new tables Most recent surveillance case definition for HIV infectionĮxplication of the concepts of innate immunity and pathogen-associated molecular patterns Update on components and physiology of normal immunity Nurses, nurse-practitioners, physician assistants, and other allied health practitioners have found that its concise format and broad scope facilitate their understanding of these basic disease entities. Practitioners (both general internists and specialists who provide generalist care) will find it beneficial as a refresher text, designed to update their knowledge of the mechanisms underlying 132 commonly encountered diseases and disorders. The book is also helpful to students engaged in their internal medicine and surgery clerkships, and to house officers as an up-to-date summary of relevant physiology and a source of key references. It is valuable to students early in their medical school years by highlighting the clinical relevance of their basic science courses, and in preparation for their USMLE Step 1 examinations. ![]() The book has proved useful as a text for both Pathophysiology and Introduction to Clinical Medicine courses in medical schools, and it has been popular in similar courses in nursing schools, physician assistants' training programs, and other allied health programs.
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